Obviously, the use of this substance increases the volume of the muscle mass by its effect similar to that of the male sex hormone…
The anabolic steroids such as Nandrolone, continue to be used among some bodybuilders to increase the volume of muscle mass and also the sports news inform us through this doping substance persists among some professional athletes.
Nadrolona decanoate (Deca-Durabolin) is used by your doctor to reduce the effects of some chronic diseases on the muscular structure of the patient and in the cases that should be dealt with the side effects of glucocorticoids or radiotherapy to improve the muscle deterioration due to some diseases or annotated substance.
However, how widespread is the inappropriate use of this substance among users of gyms and sports centres; the British Medical Journal has recently published a study among regular attendees of gyms in England, retrieved through anonymous surveys, which showed that 30% of respondents it used anabolic steroids and of them 84% regularly used Nandrolone decanoate.
Obviously, the use of this substance increases the volume of the muscle mass by its effect similar to that of the male sex hormone (androgen effect), however, the side effects of Nandrolone decanoate should be taken into account:
-In women using it may develop effects of virilization (male body structure, deepening of the voice, HIRSUTISM, acne, increased libido, etc.)
-In children, early development of puberty and premature closure of the bony cores of growth may be seen.
-Hoarseness can be one of the symptoms of thickening of the vocal cords which could result in a lasting and irreversible change of voice.
-Inhibition of sperm production can take place in men.
-In women can occur alteration of menstrual cycles, especially amenorrhea (menstrual delayed more than 45 days)
-Can occur in body fluid retention
-In people with heart failure, hypertension, epilepsy or migraine may exacerbate the symptoms.
-Possible alteration of liver function.
REPORTS OF A HEART IN A STEROIDS USER ATTACK
It seems that every month appears something new regarding adverse cardiovascular effects of anabolic steroid users. This time, the information comes from the University of California, Berkeley.
This time the information relates to a young man of 25 years, slender and muscular Constitution, without prior medical history or significant cardiovascular risk factors except a partial family history that I am presenting at the emergency room with a sharp pain in the chest, strong and distressing episode.
The patient can tell that he had been in his normal situation in good health until the morning of the test, when I noticed a severe fatigue after a heavy workout. It soon began to notice a pain in the chest and went home in his car. But the pain increased in intensity and began to radiate to the neck. He felt nauseous and he began to sweat profusely.
The individual had begun to use Nandrolone decanoate, 100 mg per week, from to 16 weeks. After injecting the dose for 6 weeks, I leave it for 4 weeks and returned to injecting, but this time 200 mg weekly. The last injection had been her 2 days before his heart attack. The reading of cholesterol at the time of their admission to the hospital was 196 mg/dl.
The patient worked well with the initial cardiac rehabilitation and could leave the hospital 13 days. After that complete 12 weeks of rehabilitation participating in vigorous aerobic activity 3 times per week. He also returned to training with weights, but with lighter loads and less intensity than it had used before. Eight months after he had suffered a heart attack, the guy seemed to have returned to normal – reporting that did not have any heart symptoms – and its analytical was within the normal range.
The specific cause of this event (coronary thrombosis) can cannot be determined with precision. However, it is suggested that steroids may have predisposed the patient to that is you produce an accumulation of blood platelet. The increase in platelet aggregation, coupled with a State induced by exercise that could promote clotting, may have been blamed for the problem.
The ability of anabolic steroids to alter the activity of blood platelets is something that should be assumed a major concern, because you can get to put in a State of risk with respect to a series of catastrophic health events, including heart attacks, strokes, and pulmonary embolism to individuals as the case is treated here, perfectly healthy and non high risk populations.
Nandrolone decanoateOil solution for intramuscular useCompositionEach ml of oil solution contains:25 or 50 mg of nandrolone decanoate.Inactive ingredients: Alcohol benzyl, peanut oil.FeaturesDeca-Durabolin is an injectable anabolic preparation. After the injection, the decanoate ofnandrolone is gradually released from the intramuscular Depot and is subsequentlyhydrolysed tonandrolone. The duration of action is approximately three weeks.Anabolic Deca-Durabolin profile has been established in human metabolic studies.Thesedemonstrated their protein–saving effects and anticatabolic, as well as its favorableeffects in thein cases of increased calcium excretion and osteoporosis calcium metabolism.It is unlikely that Deca-Durabolin produces adverse Androgenic effects (for example,virilization) at recommended doses. The dissociation of androgenic and anabolic effects isrelated to the presence or absence of 5α reductase in tissues containing receiver ofandrogen. The reduction of nandrolone 5α gives rise to the 5α dihydro-nandrolonewhich is linked to theless intensely than the same nandrolone androgen receptor. With testosterone andthe 5αdihydro-testosterone occurs in reverse. This explains the effect relatively intense of the nandrolonein tissues devoid of activity 5α reductase (for example, the muscle tissue) comparedwith theirrelatively weak effect in tissues with 5α reductase relatively high activity (for example, the)Prostate). Another important feature is that you as a result of its chemical structure,is notlikely that Deca-Durabolin has adverse effects on the liver. No cases have been described inCholestatic jaundice or hepatomas. Deca-Durabolin can be used as an adjuvant ofspecific therapies and dietary measures in various pathological processes characterized by anegative nitrogen balance. With Deca-Durabolin as an adjunct of parenteral nutrition, isthey have obtained favourable results. In patients with osteoporosis, it has been observed that Decadurabolinincreases the bone matrix, stops bone loss and reducing fracture rates. In additionIt produces a marked relief of clinical symptoms of osteoporosis, especially lumbarback pain.Indications and dosageAs an adjunct of specific therapies and dietary measures in pathological processescharacterized by a negative nitrogen balance, for example, in chronic diseasesdebilitating, during prolonged therapeutic glucocorticosteroide, during radiation therapy and aftermajor surgery and trauma.Adults:25-50 mg every 3 weeks.Children:more than 30 kg: 15 mg every 3 weeks;20-30 kg: 7.5-10 mg every 3 weeks;10-20 kg: 5-7.5 mg every 3 weeks;less than 10 kg: 5 mg every 3 weeks.Osteoporosis.50 mg every 2-3 weeks.
For the palliative treatment of selected cases of mammary carcinoma spread in women.50 mg every 2-3 weeks.Rules for proper administrationDeca-Durabolin should be administered by deep intramuscular injection.ContraindicationsPregnancy.Prostatic carcinoma or known or suspected male breast carcinoma.Precautions and warningsIf will develop signs of virilization, must consider is the interruption of the treatment.Patients with the following pathological States should be monitored.• Failure latent or manifest cardiac, renal dysfunction, hypertension, epilepsy or migraine (orhistory of these conditions) since anabolic steroids may induce timessalt and water retention.• Diabetes, since anabolic steroids may improve glucose tolerance and reduce theneeds of insulin or other antidiabetic agents.• Growth stature incomplete, since anabolic steroids at high doses can acceleratethe epiphyseal closure.• Skeletal metastases, since anabolic steroids may induce hypercalcemia andhypercalciuria in these patients.Informing athletes that this medicine contains a component that you can set aanalytical result of how positive doping control.Other sofware related with excipientsTo contain as excipient benzyl alcohol, this medication is contraindicated in childrenunder three years of age.Side effects and adverse reactionsHigh doses, prolonged treatment or too frequent administrationthey may cause:• Virilization that appears in women that are sensitive in the form of hoarseness, acne, HIRSUTISM, and increaselibido; in children before puberty in the form of an increase of the frequency of theerections and phallic thickening and as an increase of the pubic hair and hypertrophy of theclitoris. Hoarseness may be the first symptom of vocal change which can be completed in oneaggravation of the tone of the durable voice and sometimes irreversible.• Amenorrhea and inhibition of spermatogenesis.• Close premature epiphyseal.• Water and salt retention.IncompatibilitiesThey have not described.Poisoning and its treatmentAlthough there is no risk of poisoning, overdose or ingestion to the prescribed dosesaccidental, consult the toxicology information service.Phone 91 562 04 20.Storage conditionsDo not store at temperature above 30 ° C.Do not refrigerate or freeze.Keep in the outer packaging.
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